Litvintseva, Anastasia P. ; Pan, Weihua ; Khayhan, Kantarawee ; Hagen, Ferry ; Wahyuningsih, Retno ; Chakrabarti, Arunaloke ; Chowdhary, Anuradha ; Ikeda, Reiko ; Taj-Aldeen, Saad J. ; Khan, Ziauddin ; Imran, Darma ; Sjam, Ridhawati ; Sriburee, Pojana ; Liao, Wanqing ; Chaicumpar, Kunyaluk ; Ingviya, Natnicha ; Mouton, Johan W. ; Curfs-Breuker, Ilse ; Boekhout, Teun ; Meis, Jacques F. ; Klaassen, Corné H. W. (2012) Resistance of Asian Cryptococcus neoformans Serotype A Is Confined to Few Microsatellite Genotypes PLoS One, 7 (3). e32868. ISSN 1932-6203
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Official URL: http://doi.org/10.1371/journal.pone.0032868
Related URL: http://dx.doi.org/10.1371/journal.pone.0032868
Abstract
Cryptococcus neoformans is a pathogenic yeast that causes cryptococcosis, a life threatening disease. The prevalence of cryptococcosis in Asia has been rising after the onset of the AIDS epidemic and estimates indicate more than 120 cases per 1,000 HIV-infected individuals per year. Almost all cryptococcal disease cases in both immunocompromised and immunocompetent patients in Asia are caused by C. neoformans var. grubii. Epidemiological studies on C. neoformans in pan-Asia have not been reported. The present work studies the genetic diversity of the fungus by microsatellite typing and susceptibility analysis of approximately 500 isolates from seven Asian countries.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Public Library of Science. |
| ID Code: | 117578 |
| Deposited On: | 27 Apr 2021 08:27 |
| Last Modified: | 27 Apr 2021 08:27 |
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