Chowdhary, Anuradha ; Perfect, John ; de Hoog, G. Sybren (2014) Black Molds and Melanized Yeasts Pathogenic to Humans Cold Spring Harbor Perspectives in Medicine, 5 (8). a019570. ISSN 2157-1422
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Official URL: http://doi.org/10.1101/cshperspect.a019570
Related URL: http://dx.doi.org/10.1101/cshperspect.a019570
Abstract
A review is given of melanized fungi involved in human infection, including species forming budding cells and strictly filamentous representatives. Classically, they are known as “phaeoid” or “dematiaceous” fungi, and, today, agents are recognized to belong to seven orders of fungi, of which the Chaetothyriales and Pleosporales are the most important. Infections range from cutaneous or pulmonary colonization to systemic or disseminated invasion. Subcutaneous involvement, either primary or after dissemination, may lead to host tissue proliferation of dermis or epidermis. Particularly in the Chaetothyriales, subcutaneous and systemic infections may occur in otherwise apparently healthy individuals. Infections are mostly chronic and require extended antifungal therapy and/or surgery.
Item Type: | Article |
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Source: | Copyright of this article belongs to Cold Spring Harbor Laboratory. |
ID Code: | 117528 |
Deposited On: | 26 Apr 2021 10:21 |
Last Modified: | 26 Apr 2021 10:21 |
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