Fakhim, Hamed ; Chowdhary, Anuradha ; Prakash, Anupam ; Vaezi, Afsane ; Dannaoui, Eric ; Meis, Jacques F. ; Badali, Hamid (2017) In Vitro Interactions of Echinocandins with Triazoles against Multidrug-Resistant Candida auris Antimicrobial Agents and Chemotherapy, 61 (11). ISSN 0066-4804
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Official URL: http://doi.org/10.1128/AAC.01056-17
Related URL: http://dx.doi.org/10.1128/AAC.01056-17
Abstract
We determined the in vitro interactions between echinocandins and azoles against 10 multidrug-resistant Candida auris strains by use of a microdilution checkerboard technique. Our results suggest synergistic interactions between micafungin and voriconazole with fractional inhibitory concentration index (FICI) values of 0.15 to 0.5, and we observed indifferent interactions when micafungin was combined with fluconazole (FICI, 0.62 to 1.5). Combinations of caspofungin with fluconazole or voriconazole exhibited indifferent interactions. No antagonism was observed for any combination.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Society for Microbiology. |
| ID Code: | 117423 |
| Deposited On: | 21 Apr 2021 08:04 |
| Last Modified: | 21 Apr 2021 08:04 |
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