Anti-fungal activity of a novel triazole, PC1244, against emerging azole-resistant Aspergillus fumigatus and other species of Aspergillus

Colley, Thomas ; Sharma, Cheshta ; Alanio, Alexandre ; Kimura, Genki ; Daly, Leah ; Nakaoki, Takahiro ; Nishimoto, Yuki ; Bretagne, Stéphane ; Kizawa, Yasuo ; Strong, Pete ; Rapeport, Garth ; Ito, Kazuhiro ; Meis, Jacques F ; Chowdhary, Anuradha (2019) Anti-fungal activity of a novel triazole, PC1244, against emerging azole-resistant Aspergillus fumigatus and other species of Aspergillus Journal of Antimicrobial Chemotherapy, 74 (10). pp. 2950-2958. ISSN 0305-7453

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Official URL: http://doi.org/10.1093/jac/dkz302

Related URL: http://dx.doi.org/10.1093/jac/dkz302

Abstract

The growing emergence of azole-resistant Aspergillus fumigatus strains worldwide is a major concern for current systemic antifungal treatment. Here we report antifungal activities of a novel inhaled triazole, PC1244, against a collection of multi-azole-resistant A. fumigatus strains.

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ID Code:117334
Deposited On:19 Apr 2021 09:41
Last Modified:19 Apr 2021 09:41

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