Ghorai, Manas K. ; Nanaji, Y. ; Yadav, A. K. (2011) Ring Opening/C–N Cyclization of Activated Aziridines with Carbon Nucleophiles: Highly Diastereo- and Enantioselective Synthesis of Tetrahydroquinolines Organic Letters, 13 (16). pp. 4256-4259. ISSN 1523-7060
Full text not available from this repository.
Official URL: http://doi.org/10.1021/ol2016077
Related URL: http://dx.doi.org/10.1021/ol2016077
Abstract
A simple strategy for the synthesis of substituted tetrahydroquinolines through regio- and stereoselective ring opening of N-tosyl aziridines with carbon nucleophiles generated from 2-(bromoaryl)acetonitriles followed by palladium-catalyzed intramolecular C–N cyclization is reported in excellent yields (up to >99%) and stereoselectivity (ee and de up to >99%).
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 117119 |
| Deposited On: | 15 Apr 2021 08:00 |
| Last Modified: | 15 Apr 2021 08:00 |
Repository Staff Only: item control page
