Ghosh, Joydeep ; Swarup, Vivek ; Saxena, Amit ; Das, Sulagna ; Hazra, Abhijit ; Paira, Priyankar ; Banerjee, Sukdeb ; Mondal, Nirup B. ; Basu, Anirban (2008) Therapeutic effect of a novel anilidoquinoline derivative, 2-(2-methyl-quinoline-4ylamino)-N-(2-chlorophenyl)-acetamide, in Japanese encephalitis: correlation with in vitro neuroprotection International Journal of Antimicrobial Agents, 32 (4). pp. 349-354. ISSN 0924-8579
Full text not available from this repository.
Official URL: http://doi.org/10.1016/j.ijantimicag.2008.05.001
Related URL: http://dx.doi.org/10.1016/j.ijantimicag.2008.05.001
Abstract
2-(2-Methyl-quinoline-4ylamino)-N-(2-chlorophenyl)-acetamide, a novel anilidoquinoline derivative, was synthesised and evaluated for its therapeutic efficacy in treating Japanese encephalitis. The compound showed significant antiviral and antiapoptotic effects in vitro. Significant decreases in viral load (P < 0.01) combined with an increase in survival was observed in Japanese encephalitis virus-infected mice treated with 2-(2-methyl-quinoline-4ylamino)-N-(2-chlorophenyl)-acetamide.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier B.V. |
| Keywords: | Anilidoquinoline; Japanese Encephalitis Virus; Neuron; Apoptosis; Tunel. |
| ID Code: | 115663 |
| Deposited On: | 18 Mar 2021 04:35 |
| Last Modified: | 22 Mar 2021 06:57 |
Repository Staff Only: item control page
