Mohapatra, Debendra K. ; Pramanik, Chinmoy ; Chorghade, Mukund S. ; Gurjar, Mukund K. (2007) A short and efficient synthetic strategy for the total syntheses of (S)-(+)-and (R)-(−)-plakolide A European Journal of Organic Chemistry, 2007 (30). pp. 5059-5063. ISSN 1434-193X
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Official URL: http://www3.interscience.wiley.com/journal/1148012...
Related URL: http://dx.doi.org/10.1002/ejoc.200700401
Abstract
Concise and efficient total syntheses of anticancer agents (S)-(+)-Plakolide A and (R)-(−)-Plakolide A were accomplished in eight steps and an overall yield of 39% starting from geraniol. The key steps in our strategy are Sharpless asymmetric epoxidation, double elimination, and Stille coupling reactions.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons, Inc. |
| Keywords: | Inhibitors; Epoxidation; Olefination; Cross-coupling |
| ID Code: | 11463 |
| Deposited On: | 16 Nov 2010 13:56 |
| Last Modified: | 02 Jun 2011 09:38 |
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