Khajamohiddin, Syed ; Repalle, Elisha Raju ; Pinjari, Aleem Basha ; Merrick, Mike ; Siddavattam, Dayananda (2008) Biodegradation of aromatic compounds: An overview of Meta Fission Product hydrolases Critical Reviews in Microbiology, 34 (1). pp. 13-31. ISSN 1040-841X
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Official URL: https://www.tandfonline.com/doi/abs/10.1080/104084...
Related URL: http://dx.doi.org/10.1080/10408410701683656
Abstract
Meta Fission Product (MFP) hydrolases catalyze hydrolysis of a low reactive carbon-carbon bond found in Meta Fission Products, generated during biodegradation of various aromatic compounds. These enzymes belong to the alpha/beta hydrolase super family and show structural conservation despite having poor sequence similarity. MFP-hydrolases are substrate specific and studies have indicated that this substrate specificity plays a key role in the determination of the organism's ability to degrade a particular substrate. In this concise review of MFP-hydrolases we discuss their classification, biochemical properties, the molecular basis of their substrate specificity, their catalytic mechanism and evolutionary significance.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Taylor & Francis Group. |
| Keywords: | Meta Fission Product Hydrolase, CumD, Meta-cleavage Pathway, Ortho-cleavage Pathway |
| ID Code: | 114197 |
| Deposited On: | 28 May 2018 06:20 |
| Last Modified: | 28 May 2018 06:20 |
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