Naik, Sarala ; Bhattacharjya, Gitalee ; Talukdar, Bandana ; Patel, Bhisma K. (2004) Chemoselective acylation of amines in aqueous media European Journal of Organic Chemistry, 2004 (6). pp. 1254-1260. ISSN 1434-193X
Full text not available from this repository.
Official URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/ej...
Related URL: http://dx.doi.org/10.1002/ejoc.200300620
Abstract
Amines are efficiently acylated by both cyclic and acyclic anhydrides by dissolving them in an aqueous medium with the help of a surfactant, Sodium Dodecyl Sulfate (SDS). Cyclic and acyclic anhydrides react with equal ease with an amine, and amines with various stereo‐electronic factors react at the same rates with an anhydride. Chemoselective acylation of amines in the presence of phenols and thiols and of thiols in the presence of phenols has been achieved. No acidic or basic reagents are used during the reaction. No chromatographic separation is required for isolation of the acylated products. Reactions in a neutral aqueous medium, easy isolation of products, and innocuous by‐products make the present method a green chemical process.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | Amines; Amides; Acylation; Aqueous Media; Chemoselectivity |
| ID Code: | 113969 |
| Deposited On: | 30 Apr 2018 12:14 |
| Last Modified: | 30 Apr 2018 12:14 |
Repository Staff Only: item control page
