A one-pot conversion of di-substituted thiourea toO-organyl arylthiocarbamate using FeCl3

Sahoo, Santosh K. ; Chakraborty, Supratim ; Patel, Bhisma K. (2012) A one-pot conversion of di-substituted thiourea toO-organyl arylthiocarbamate using FeCl3 Journal of Sulfur Chemistry, 33 (2). pp. 143-153. ISSN 1741-5993

Full text not available from this repository.

Official URL: https://www.tandfonline.com/doi/abs/10.1080/174159...

Related URL: http://dx.doi.org/10.1080/17415993.2011.640328

Abstract

Unsymmetrical thiourea, which on demand can generate isothiocyanate in the presence of FeCl3, can serve as a latent isothiocyanate functionality and circumvent the difficulties associated with the direct use of reactive isothiocyanate functionality. An unusual and unorthodox reactivity has been achieved during a one-pot reaction of an unsymmetrically di-substituted thiourea with an alcohol in the presence of FeCl3 leading to an expeditious synthesis of O-organyl arylthiocarbamates. In this reaction, a thiono-ester (C‒O) bond is formed at the expense of a thioamidic (C‒N) bond and works over a wide range of structurally diverse thioureas and alcohols without affecting the other functional groups.

Item Type:Article
Source:Copyright of this article belongs to Taylor and Francis Group
Keywords:Green Chemistry; Thiourea; Fe-catalyst; Arylthiocarbamate; C‒O Bond
ID Code:113908
Deposited On:02 May 2018 04:49
Last Modified:02 May 2018 04:49

Repository Staff Only: item control page