Mahale, Rajendra D. ; Rajput, Mahesh R. ; Maikap, Golak C. ; Gurjar, Mukund K. (2010) Davis oxaziridine-mediated asymmetric synthesis of proton pump inhibitors using DBU salt of prochiral sulfide Organic Process Research & Development, 14 (5). pp. 1264-1268. ISSN 1083-6160
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Official URL: http://pubs.acs.org/doi/abs/10.1021/op100075v
Related URL: http://dx.doi.org/10.1021/op100075v
Abstract
A simple and clean asymmetric synthesis of proton pump inhibitors using inexpensive 10-camphorsulfonyl oxaziridine is described. Here, we report the activation of prochiral sulfide by making the DBU salt that is capable of enhancing the reactivity and enantioselectivity.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 11390 |
| Deposited On: | 09 Nov 2010 05:38 |
| Last Modified: | 02 Jun 2011 09:35 |
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