Gogoi, Anupal ; Guin, Srimanta ; Rout, Saroj K. ; Majji, Ganesh ; Patel, Bhisma K. (2014) A Cu-catalysed synthesis of substituted 3-methyleneisoindolin-1-one RSC Advances, 4 (104). pp. 59902-59907. ISSN 2046-2069
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Official URL: http://pubs.rsc.org/en/content/articlelanding/2014...
Related URL: http://dx.doi.org/10.1039/C4RA12782J
Abstract
A Cu(I)-catalysed synthesis of substituted 3-methyleneisoindolin-1-ones using alkynyl acids as an alkyne source has been developed. The reaction involves the decarboxylative cross-coupling of 2-halobenzamides with aryl alkynyl acids, followed by 5-exo-dig heteroannulation. While reactions of 2-iodo benzamides proceeded without a ligand, for 2-bromo substrates, the assistance of a ligand is essential.
Item Type: | Article |
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Source: | Copyright of this article belongs to Royal Society of Chemistry. |
ID Code: | 113858 |
Deposited On: | 30 Apr 2018 12:11 |
Last Modified: | 30 Apr 2018 12:11 |
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