Chandra, Goutam ; Ghosh, Kalyan S. ; Dasgupta, Swagata ; Roy, Anushree (2010) Evidence of conformational changes in adsorbed lysozyme molecule on silver colloids International Journal of Biological Macromolecules, 47 (3). pp. 361-365. ISSN 0141-8130
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Official URL: https://www.sciencedirect.com/science/article/pii/...
Related URL: http://dx.doi.org/10.1016/j.ijbiomac.2010.05.020
Abstract
In this article, we discuss metal–protein interactions in the Ag–lysozyme complex by spectroscopic measurements. The analysis of the variation in relative intensities of SERS bands reveals the orientation and the change in conformation of the protein molecules on the Ag surface with time. The interaction kinetics of metal–protein complexes has been analyzed over a period of 3 h via Raman measurements. Our analysis indicates that the Ag nanoparticles most likely interact with Trp123 which is in close proximity to Phe34 of the lysozyme molecule.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Lysozyme; Ag Colloids; SERS |
| ID Code: | 113501 |
| Deposited On: | 15 May 2018 11:19 |
| Last Modified: | 15 May 2018 11:19 |
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