A highly selective fluorescent probe for detection of hydrogen sulfide in living systems: In vitro and in vivo applications

Reja, Shahi Imam ; Sharma, Neetu ; Gupta, Muskan ; Bajaj, Payal ; Bhalla, Vandana ; Parihar, Ripu D. ; Ohri, Puja ; Kaur, Gurcharan ; Kumar, Manoj (2017) A highly selective fluorescent probe for detection of hydrogen sulfide in living systems: In vitro and in vivo applications Chemistry - A European Journal, 23 (41). pp. 9872-9878. ISSN 0947-6539

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Official URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/ch...

Related URL: http://dx.doi.org/10.1002/chem.201701124

Abstract

A fluorescein‐based fluorescent probe has been designed and synthesised that selectively detects H2S in aqueous medium, among various analytes tested. This fluorescein‐based fluorescent probe has also been successfully utilised for real‐time imaging of exo‐ and endogenously produced H2S in cancer cells and normal cells. Moreover, the probe can also detect H2S in the rat brain hippocampus at variable depths and in living nematodes.

Item Type:Article
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ID Code:113363
Deposited On:16 May 2018 08:29
Last Modified:16 May 2018 08:29

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