Sharma, Neetu ; Reja, Shahi Imam ; Gupta, Neha ; Bhalla, Vandana ; Kaur, Davinder ; Arora, Saroj ; Kumar, Manoj (2017) A highly selective fluorescent probe for Fe3+ in living cells: a stress induced cell based model study Organic and Biomolecular Chemistry, 15 (4). pp. 1006-1012. ISSN 1477-0520
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Official URL: http://pubs.rsc.org/en/content/articlelanding/2017...
Related URL: http://dx.doi.org/10.1039/C6OB02209J
Abstract
A rhodamine–phenanthroline dyad based fluorescent probe 4 has been designed and synthesized which selectively monitors Fe3+ ions among the various metal ions tested. Furthermore, probe 4 has been explored for monitoring of dynamic changes in the Fe3+ ion level under aggressive Fenton reaction conditions using a cell based model study. More significantly, probe 4 has also been utilized for real time imaging of endogenous Fe3+ ions in living C6 cell lines, the results of which demonstrated that probe 4 acts as an efficient fluorescent tool for Fe3+ ion detection in biological systems.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 113359 |
| Deposited On: | 16 May 2018 07:00 |
| Last Modified: | 16 May 2018 07:00 |
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