A lysosome targetable fluorescent probe for endogenous imaging of hydrogen peroxide in living cells

Reja, Shahi Imam ; Gupta, Muskan ; Gupta, Neha ; Bhalla, Vandana ; Ohri, Puja ; Kaur, Gurcharan ; Kumar, Manoj (2017) A lysosome targetable fluorescent probe for endogenous imaging of hydrogen peroxide in living cells Chemical Communications, 53 (26). pp. 3701-3704. ISSN 1359-7345

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Official URL: http://pubs.rsc.org/en/content/articlelanding/2017...

Related URL: http://dx.doi.org/10.1039/C6CC09127J

Abstract

A lysosome targetable naphthalimide based fluorescent probe (LyNC) has been designed and synthesized which detects hydrogen peroxide (H2O2) with high selectivity and sensitivity in brain tissues and in living nematodes among various ROS/RNS tested. Further, the probe LyNC was successfully employed in exogenous and endogenous imaging of H2O2 in living cell lines.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:113332
Deposited On:16 May 2018 06:54
Last Modified:16 May 2018 06:54

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