A targeted, image-guided and dually locked photoresponsive Drug Delivery System

Karthik, S. ; Prashanth Kumar, B. N. ; Gangopadhyay, Moumita ; Mandal, Mahitosh ; Pradeep Singh, N. D. (2015) A targeted, image-guided and dually locked photoresponsive Drug Delivery System Journal of Materials Chemistry B, 3 (5). pp. 728-732. ISSN 2050-750X

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Official URL: http://pubs.rsc.org/en/content/articlelanding/2015...

Related URL: http://dx.doi.org/10.1039/C4TB01583E

Abstract

We have developed a new targeted image-guided photoresponsive Drug Delivery System (DDS) based on a dual locking strategy. Excitation of the DDS by fluorescent light results in the first unlocking and activation of the drug, and allows real-time monitoring of the prodrug. Extended irradiation results in a second unlocking, giving drug release within cancer cells.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:113102
Deposited On:07 May 2018 12:02
Last Modified:07 May 2018 12:02

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