Sen, Kacoli ; Mandal, Mahitosh (2013) Second generation liposomal cancer therapeutics: Transition from laboratory to clinic International Journal of Pharmaceutics, 448 (1). pp. 28-43. ISSN 0378-5173
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Official URL: https://www.sciencedirect.com/science/article/pii/...
Related URL: http://dx.doi.org/10.1016/j.ijpharm.2013.03.006
Abstract
Recent innovations and developments in nanotechnology have revolutionized cancer therapeutics. Engineered nanomaterials are the current workhorses in the emerging field of cancer nano-therapeutics. Lipid vesicles bearing anti-tumor drugs have turned out to be a clinically feasible and promising nano-therapeutic approach to treat cancer. Efficient entrapment of therapeutics, biocompatibility, biodegradability, low systemic toxicity, low immunogenicity and ability to bypass multidrug resistance mechanisms has made liposomes a versatile drug/gene delivery system in cancer chemotherapy. The present review attempts to explore the recent key advances in liposomal research and the vast arsenal of liposomal formulations currently being utilized in treatment and diagnosis of cancer.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Liposomes; Cancer Therapeutics; Drug Delivery; Second Generation |
| ID Code: | 112986 |
| Deposited On: | 09 May 2018 09:04 |
| Last Modified: | 09 May 2018 09:04 |
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