Chandra Rai, Ramesh ; Dwivedi, Ved Prakash ; Chatterjee, Samit ; Raghava Prasad, Durbaka Vijaya ; Das, Gobardhan (2012) Early secretory antigenic target-6 of Mycobacterium tuberculosis: enigmatic factor in pathogen–host interactions Microbes and Infection, 14 (13). pp. 1220-1226. ISSN 1286-4579
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Official URL: https://www.sciencedirect.com/science/article/pii/...
Related URL: http://dx.doi.org/10.1016/j.micinf.2012.07.019
Abstract
T helper (Th) 1 and 17 cells play important roles in host protective responses against tuberculosis. Early Secretory Antigenic Target 6; a Region of Difference 1 (RD1) encoded protein, mounts Th17-responses in the lung. Therefore, lack of RD-1 region makes Bacillus Calmette–Guérin (BCG) less vaccine efficacious than parent strains.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Mycobacterium Tuberculosis; BCG; RD-1; ESAT6; CFP10; Innate/Adaptive Immunity |
| ID Code: | 112932 |
| Deposited On: | 05 Jun 2018 11:00 |
| Last Modified: | 05 Jun 2018 11:00 |
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