Gene expression profiles of wild-type and isoniazid-resistant strains of Mycobacterium smegmatis

Padiadpu, Jyothi ; Baloni, Priyanka ; Chandra, Nagasuma (2015) Gene expression profiles of wild-type and isoniazid-resistant strains of Mycobacterium smegmatis Data in Brief, 4 . pp. 186-189. ISSN 2352-3409

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Official URL: https://www.sciencedirect.com/science/article/pii/...

Related URL: http://dx.doi.org/10.1016/j.dib.2015.05.006

Abstract

The global variations in the gene expression pattern of drug treated (½X) and laboratory evolved drug-resistant strains (2XR and 4XR) of Mycobacterium smegmatis were obtained and compared with the M. smegmatis mc2 155 (WT) strain. The genes exhibiting two-fold change and p-value <0.05 under the treated conditions have been considered as differentially expressed genes (DEGs). Overall, the numbers of DEGs observed are 1529 in ½X (596—up, 933—down), 1381 (899—up, 482—down) in 2XR and 716 in 4XR (267—up, 449—down) conditions. The data is publicly available through the GEO database with accession number GSE64132.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:112646
Deposited On:19 Apr 2018 05:20
Last Modified:19 Apr 2018 05:20

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