Sarkar, Koushik ; Dastidar, Parthasarathi (2018) Supramolecular hydrogel derived from a C3-symmetric boronic acid derivative for stimuli-responsive release of insulin and doxorubicin Langmuir, 34 (2). pp. 685-692. ISSN 0743-7463
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Official URL: https://pubs.acs.org/doi/10.1021/acs.langmuir.7b03...
Related URL: http://dx.doi.org/10.1021/acs.langmuir.7b03326
Abstract
A C3-symmetric triazine based triboronic acid (HG1) was designed and synthesized. HG1 was found to give hydrogel in DMSO–water (1:9). The hydrogel was rheo-reversible and thermoreversible over a few cycles. Single-crystal X-ray diffraction (SXRD) studies on the crystals of HG1 established the presence of honeycomb network in which solvent molecules (DMSO and water) were occluded. SXRD data corroborated well with the hypothesis based on which HG1 was designed. Stimuli responsive release (in vitro) of insulin and doxorubicin from the hydrogel was also achieved.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 112527 |
| Deposited On: | 19 Apr 2018 11:46 |
| Last Modified: | 19 Apr 2018 11:46 |
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