Sengupta, Sagar ; Harris, Curtis C. (2005) p53: traffic cop at the crossroads of DNA repair and recombination Nature Reviews Molecular Cell Biology, 6 . pp. 44-55. ISSN 1471-0072
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Official URL: http://www.nature.com/nrm/journal/v6/n1/execsumm/n...
Related URL: http://dx.doi.org/10.1038/nrm1546
Abstract
p53 mutants that lack DNA-binding activities, and therefore, transcriptional activities, are among the most common mutations in human cancer. Recently, a new role for p53 has come to light, as the tumour suppressor also functions in DNA repair and recombination. In cooperation with its function in transcription, the transcription-independent roles of p53 contribute to the control and efficiency of DNA repair and recombination.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Nature Publishing Group. |
| ID Code: | 111496 |
| Deposited On: | 31 Jan 2018 09:37 |
| Last Modified: | 31 Jan 2018 09:37 |
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