Saccharin as a salt former. Enhanced solubilities of saccharinates of active pharmaceutical ingredients

Bhatt, Prashant M. ; Ravindra, Nittala V. ; Banerjee, Rahul ; Desiraju, Gautam R. (2005) Saccharin as a salt former. Enhanced solubilities of saccharinates of active pharmaceutical ingredients Chemical Communications (8). pp. 1073-1075. ISSN 1359-7345

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Official URL: http://pubs.rsc.org/en/Content/ArticleLanding/2005...

Related URL: http://dx.doi.org/10.1039/B416137H

Abstract

Saccharin, acting as a weak acid, forms salts with basic APIs and these salts have the desirable property of enhanced water solubility.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:11139
Deposited On:09 Nov 2010 03:53
Last Modified:16 May 2016 20:38

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