Sahoo, Ranjit Kumar ; Kumar, Lalit ; Kumar, Rajive ; Sharma, Atul (2013) Acute promyelocytic leukemia relapsing into acute myeloid leukemia-M2 with normal cytogenetics Indian Journal of Medical and Paediatric Oncology, 34 (4). pp. 327-329. ISSN 0971-5851
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Official URL: http://www.ijmpo.org/text.asp?2013/34/4/327/125261
Related URL: http://dx.doi.org/10.4103/0971-5851.125261
Abstract
The use of all trans-retinoic acid (ATRA) and combination chemotherapy has made acute promyelocytic leukemia (APL) a potentially curable leukemia. Late sequelae of the treatment of APL have therefore become an important consideration in the overall treatment strategy. We report a patient with APL who achieved complete clinical and molecular remission after treatment with daunorubicin and ATRA. Three years later, she developed acute myeloid leukemia (AML), M2 subtype without any evidence of relapse of the APL clone. Karyotypic analysis showed a normal female karyotype.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Wolters Kluwer. |
| Keywords: | Acute Promyelocytic Leukemia; Acute Myeloid Leukemia (AML); Secondary AML; Therapy Related AML |
| ID Code: | 111258 |
| Deposited On: | 25 Sep 2017 12:40 |
| Last Modified: | 25 Sep 2017 12:40 |
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