Siddiqui, K. A. I. ; Ghosh, Amit (1983) Temperate phage induction and filament formation in Vibrio cholerae by furazolidone Biochemical and Biophysical Research Communications, 112 (3). pp. 1106-1111. ISSN 0006-291X
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Official URL: http://dx.doi.org/10.1016/0006-291X(83)91732-1
Related URL: http://dx.doi.org/10.1016/0006-291X(83)91732-1
Abstract
Furazolidone a synthetic nitrofuran used in the treatment of cholera, was found to cause prophage induction and filament formation in Vibrio cholerae. Maximum induction of phage beta was obtained at a drug concentration of 0.5 μ g/ml. Neither induction of prophage nor filamentation took place if the drug treatment was carried out in the presence of 2.5 μ g/ml chloramphenicol, indicating a requirement for de novo protein synthesis. Our results strongly suggest the existence of "SOS" type functions in Vibrio cholerae.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 11096 |
| Deposited On: | 09 Nov 2010 04:07 |
| Last Modified: | 12 Feb 2011 03:53 |
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