Swaminathan, S. ; Raghavan, A. ; Duraipandian, M. ; Kripasankar, A. S. ; Ramachandran, P. (2005) Short-course chemotherapy for paediatric respiratory tuberculosis: 5-year report The International Journal of Tuberculosis and Lung Disease, 9 (6). pp. 693-696. ISSN 1027-3719
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Official URL: http://www.ingentaconnect.com/contentone/iuatld/ij...
Abstract
This report presents the 5-year follow-up of 137 children with respiratory tuberculosis enrolled in a randomised clinical trial of two different anti-tuberculosis regimens 9HR and 2HRZ3/4RH2. Both regimens had similar cure rates, with low relapse rates and mortality. Of 134 children followed up to 5 years, 86% had normal radiographs, with more sequelae in the 9HR group (15% vs. 1.5%, P < 0.01). One patient relapsed and there was one accidental death. Short-course chemotherapy in children is safe, effective and well tolerated, and leads to excellent long-term results, with a small proportion of children left with radiological sequelae.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to The International Union Against Tuberculosis & Lung Disease. |
| Keywords: | Paediatric; Randomised Clinical Trial; Short-Course Chemotherapy; Tuberculosis |
| ID Code: | 109893 |
| Deposited On: | 01 Sep 2017 09:12 |
| Last Modified: | 01 Sep 2017 09:12 |
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