Pathak, Divya ; Mallik, Roop (2017) Lipid-motor interactions: soap opera or symphony? Current Opinion in Cell Biology, 44 . pp. 79-85. ISSN 0955-0674
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.ceb.2016.09.005
Abstract
Intracellular transport of organelles can be driven by multiple motor proteins that bind to the lipid membrane of the organelle and work as a team. We review present knowledge on how lipids orchestrate the recruitment of motors to a membrane. Looking beyond recruitment, we also discuss how heterogeneity and local mechanical properties of the membrane may influence function of motor-teams. These issues gain importance because phagocytosed pathogens use lipid-centric strategies to manipulate motors and survive in host cells.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
ID Code: | 109338 |
Deposited On: | 10 Oct 2017 13:22 |
Last Modified: | 10 Oct 2017 13:22 |
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