Meena, ; Kumar, V. A. ; Ganesh, K. N. (2001) Synthesis and evaluation of prolyl carbamate nucleic acids (PrCNA) Nucleosides, Nucleotides and Nucleic Acids, 20 (4-7). pp. 1193-1196. ISSN 1525-7770
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Official URL: http://www.informaworld.com/smpp/content~db=all~co...
Related URL: http://dx.doi.org/10.1081/NCN-100002517
Abstract
Carbamate linked prolyl nucleic acids are obtained in high yield and purity under mild conditions in solution and solid phase. p-Nitrophenylchloroformate is used as the activating reagent for alcohol. Homooligomers of PrCNA do not bind to DNA. The introduction of this modification in PNA sequences destabilizes the triplxes, inspite of enhancement in the base stacking.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Taylor and Francis Ltd. |
| ID Code: | 10858 |
| Deposited On: | 09 Nov 2010 04:41 |
| Last Modified: | 31 May 2011 09:29 |
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