Lonkar, P. S. ; Kumar, V. A. ; Ganesh, K. N. (2001) Constrained flexibility in PNA: DNA binding studies with bridged aminopropylglycyl PNA Nucleosides, Nucleotides and Nucleic Acids, 20 (4-7). pp. 1197-1200. ISSN 1525-7770
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Related URL: http://dx.doi.org/10.1081/NCN-100002518
Abstract
Introduction of methylene bridges in aegPNA and apgPNA molecules give rise to cyclic five and six membered ring structures. Synthesis of a new six membered cyclic PNA monomer, aminopipecolyl PNA (pipPNA) is reported. Incorporation of pipPNA into PNA oligomers and comparative binding with target DNA sequences is studied.
Item Type: | Article |
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Source: | Copyright of this article belongs to Taylor and Francis Ltd. |
ID Code: | 10857 |
Deposited On: | 09 Nov 2010 04:41 |
Last Modified: | 31 May 2011 09:28 |
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