Kumar, V. A. ; D'Costa, M. ; Ganesh, K. N. (2001) Engineering preferences of hairpin PNA binding to complementary DNA: effect of N7G in aeg/aep PNA backbone Nucleosides, Nucleotides and Nucleic Acids, 20 (4-7). pp. 1187-1191. ISSN 1525-7770
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Related URL: http://dx.doi.org/10.1081/NCN-100002516
Abstract
AegPNA and aepPNA monomeric units bearing the N7-guanine nucleobase as a substitute for C+ have been demonstrated to bind to a GC base-pair of a duplex in a pH-independent manner when placed in the third strand. The aepPNA backbone exerts a preference for binding in the antiparallel Hoogsteen mode over the parallel Hoogsteen mode.
Item Type: | Article |
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Source: | Copyright of this article belongs to Taylor and Francis Ltd. |
ID Code: | 10853 |
Deposited On: | 09 Nov 2010 04:41 |
Last Modified: | 31 May 2011 09:29 |
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