D'Costa, Moneesha ; Kumar, Vaijayanti A. ; Ganesh, Krishna N. (1999) Aminoethylprolyl peptide nucleic acids (aepPNA): chiral PNA analogues that form highly stable DNA:aepPNA2 triplexes Organic Letters, 1 (10). pp. 1513-1516. ISSN 1523-7060
Full text not available from this repository.
Official URL: http://pubs.acs.org/doi/abs/10.1021/ol990835i
Related URL: http://dx.doi.org/10.1021/ol990835i
Abstract
The replacement of the glycyl component in the peptide nucleic acid (PNA) backbone by a prolyl unit bearing a nucleobase leads to the aminoethylprolyl (aep) PNAs, which are chiral and cationic. The homooligomeric aepPNA binds to complementary DNA sequences with high affinity and sequence specificity, forming highly stable triplexes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 10805 |
| Deposited On: | 09 Nov 2010 04:50 |
| Last Modified: | 31 May 2011 09:47 |
Repository Staff Only: item control page
