Isothermal titration calorimetry studies on the binding of DNA bases and PNA base monomers to gold nanoparticles

Gourishankar, A. ; Shukla, Sourabh ; Ganesh, Krishna N. ; Sastry, Murali (2004) Isothermal titration calorimetry studies on the binding of DNA bases and PNA base monomers to gold nanoparticles Journal of the American Chemical Society, 126 (41). pp. 13186-13187. ISSN 0002-7863

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ja046785g

Related URL: http://dx.doi.org/10.1021/ja046785g

Abstract

An isothermal titration calorimetric (ITC) investigation of the interaction of DNA bases and PNA base monomers with gold nanoparticles is described revealing a binding sequence in the order C > G > A > T. Direct measurement of the strength of interaction of ligands with nanogold by ITC has important implications in surface modification strategies for biomedical, catalysis, and nanoarchitecture applications.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:10794
Deposited On:09 Nov 2010 04:53
Last Modified:31 May 2011 09:37

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