Sonam, Kothari ; Bindu, P. S. ; Gayathri, Narayanappa ; Khan, Nahid Akhtar ; Govindaraju, C. ; Arvinda, Hanumanthapura R. ; Nagappa, Madhu ; Sinha, Sanjib ; Thangaraj, K. ; Taly, Arun B. (2014) The “Double Panda” sign in Leigh disease Journal of Child Neurology, 29 (7). pp. 980-982. ISSN 0883-0738
Full text not available from this repository.
Official URL: http://journals.sagepub.com/doi/abs/10.1177/088307...
Related URL: http://dx.doi.org/10.1177/0883073813484968
Abstract
Although the “face of the giant panda” sign on magnetic resonance imaging (MRI) is traditionally considered to be characteristic of Wilson disease, it has also been reported in other metabolic disorders. This study describes the characteristic “giant panda” sign on MRI in a child with Leigh disease. The diagnosis was based on the history of neurological regression; examination findings of oculomotor abnormalities, hypotonia, and dystonia; raised serum lactate levels; and characteristic brain stem and basal ganglia signal changes on MRI. The midbrain and pontine tegmental signal changes were consistent with the “face of the giant panda and her cub” sign. In addition to Wilson disease, metabolic disorders such as Leigh disease should also be considered in the differential diagnosis of this rare imaging finding.
Item Type: | Article |
---|---|
Source: | Copyright of this article belongs to Sage Publications. |
ID Code: | 107763 |
Deposited On: | 01 Feb 2018 11:46 |
Last Modified: | 01 Feb 2018 11:46 |
Repository Staff Only: item control page