Gopalakrishnan, R. ; Subramanian, V. (2011) Interaction of collagen with carbon nanotube: a molecular dynamics investigation Journal of Biomedical Nanotechnology, 7 (1). pp. 186-187. ISSN 1550-7033
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Official URL: http://www.ingentaconnect.com/contentone/asp/jbn/2...
Related URL: http://dx.doi.org/10.1166/jbn.2011.1261
Abstract
In variety of biological applications carbon nano materials interact with different biological macromolecules, such as proteins, carbohydrates and nucleic acids. In this study carbon nanotube (CNT) has been used as the model for carbon nanomaterials. Since, collagen is a large protein; model collagen like peptide (CPs) has been used to understand the interaction between CNT and collagen. Molecular dynamics (MD) simulation showed that the hydrophobic–hydrophobic interaction of the CNT-CPs play a crucial role in attracting the CPs towards the CNT. No structural aberrations occured in collagen upon interaction with CNT and hence CNT can be employed in the tissue engineering applications.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Scientific Publishers. |
| Keywords: | Carbon Nanotube (Cnt); Collagen Like Peptides (Cps); Extra Cellular Matrix (Ecm); Molecular Dynamics (Md) Simulation; Toxicity |
| ID Code: | 107286 |
| Deposited On: | 01 Dec 2017 12:31 |
| Last Modified: | 01 Dec 2017 12:31 |
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