Tandon, N. ; Shtauvere-Brameus, A. ; Hagopian, W. A. ; Sanjeevi, C. B. (2006) Prevalence of ICA-12 and other autoantibodies in north Indian patients with early-onset diabetes Annals of the New York Academy of Sciences, 958 (1). pp. 214-217. ISSN 0077-8923
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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1749-...
Related URL: http://dx.doi.org/10.1111/j.1749-6632.2002.tb02972.x
Abstract
This study attempts to assess the prevalence of various autoantibodies in early-onset diabetics in northern India, with emphasis on antibodies against glutamic acid decarboxylase (GAD65), IA-2, ICA-12, 21-hydroxylase (21-OH) and Tissue Transglutaminase (TTG). GAD65 and IA-2 antibodies were found to be present in approximately 26% of cases of type 1 diabetes. A subset of patients clinically diagnosed to have MMDM appears to have an autoimmune etiology, with more than 20% showing serpositivity for IA-2 antibodies. Antibodies against ICA-12 were prevalent in both type 1 diabetes and MMDM. Approximately one of seven patients with type 1 diabetes showed erological evidence of celiac disease.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons Inc. |
| ID Code: | 107089 |
| Deposited On: | 23 Jun 2017 06:40 |
| Last Modified: | 23 Jun 2017 06:41 |
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