A novel tandem sequence to pyrrole syntheses by 5-endo-digcyclization of 1,3-enynes with amines

Bharathiraja, Ganesan ; Sakthivel, Sekarpandi ; Sengoden, Mani ; Punniyamurthy, Tharmalingam (2013) A novel tandem sequence to pyrrole syntheses by 5-endo-digcyclization of 1,3-enynes with amines Organic Letters, 15 (19). pp. 4996-4999. ISSN 1523-7060

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ol402305b

Related URL: http://dx.doi.org/10.1021/ol402305b

Abstract

The synthesis of pentasubstituted pyrroles has been described using molecular iodine from 1,3-enynes and amines via a sequential tandem aza-Michael addition, iodocyclization, and oxidative aromatization. The protocol is simple and efficient to afford the target products at ambient conditions.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:106670
Deposited On:22 Jun 2017 10:09
Last Modified:22 Jun 2017 10:09

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