Guru, Murali Mohan ; Punniyamurthy, Tharmalingam (2012) Copper(II)-catalyzed aerobic oxidative synthesis of substituted 1,2,3- and 1,2,4-triazoles from bisarylhydrazones via C–H functionalization/C–C/N–N/C–N bonds formation The Journal of Organic Chemistry, 77 (11). pp. 5063-5073. ISSN 0022-3263
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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo300592t
Related URL: http://dx.doi.org/10.1021/jo300592t
Abstract
An unprecedented copper(II)-catalyzed aerobic oxidative synthesis of 2,4,5-triaryl-1,2,3-triazoles and 1,3,5-triaryl-1,2,4-triazoles from bisarylhydrazones as the common starting precursor has been achieved via cascade C–H functionalization/C–C/N–N/C–N bonds formation under mild reaction conditions. One of the enthralling outcomes of this strategy is the copper(II)-catalyzed room temperature C–H functionalization/C–N bond formation in presence of air, which has been accomplished during the synthesis of substituted 1,2,4-triazoles. This new class of compounds could give prospective luminescence as an iconic component in the area of pharmaceutical and biological sciences. The intermediates for both the processes have been isolated to elucidate the mechanistic scenario.
Item Type: | Article |
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Source: | Copyright of this article belongs to American Chemical Society. |
ID Code: | 106590 |
Deposited On: | 22 Jun 2017 10:15 |
Last Modified: | 22 Jun 2017 10:15 |
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