Dururgkar, Kulbhushan A. ; Gonnade, Rajesh G. ; Ramana, C. V. (2009) A Cu(I)-promoted one-pot ‘SNAr–click reaction’ of fluoronitrobenzenes Tetrahedron, 65 (20). pp. 3974-3979. ISSN 0040-4020
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tet.2009.03.035
Abstract
A one-pot two-step sequence involving a nucleophilic aromatic substitution (SNAr) of activated fluorobenzenes with azide nucleophile and in situ Huisgen cycloaddition of the resulting aryl azides with alkynes has been developed for a rapid access to 1,4-substituted triazoles. Control experiments revealed that both the steps are catalyzed by Cu(I) and also the course of reaction as SNAr followed by [3+2]-cycloaddition.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
ID Code: | 106140 |
Deposited On: | 01 Feb 2018 16:55 |
Last Modified: | 01 Feb 2018 16:55 |
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