Sulfinimine-mediated asymmetric synthesis of β-hydroxy α-amino phosphonates

Davis, Franklin A. ; Prasad, Kavirayani R. (2003) Sulfinimine-mediated asymmetric synthesis of β-hydroxy α-amino phosphonates The Journal of Organic Chemistry, 68 (19). pp. 7249-7253. ISSN 0022-3263

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo0301649

Related URL: http://dx.doi.org/10.1021/jo0301649

Abstract

The addition of potassium dialkyl phosphites to enantiopure O-protected α-hydroxy sulfinimine pseudoenantiomers affords β-hydroxy α-amino phosphonates in good yield and de. The reaction exhibits a strong match−mismatch effect.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:106022
Deposited On:21 Dec 2017 12:02
Last Modified:21 Dec 2017 12:02

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