Synthesis and structural characterization of homochiral homo-oligomers of cis-γ-methoxy-substituted cis- and trans-furanoid-β-amino acids

Giri, Awadut G. ; Jogdand, Ganesh F. ; Rajamohanan, Pattuparampil R. ; Pandey, Sunil K. ; Ramana, Chepuri V. (2012) Synthesis and structural characterization of homochiral homo-oligomers of cis-γ-methoxy-substituted cis- and trans-furanoid-β-amino acids European Journal of Organic Chemistry, 2012 (13). pp. 2656-2663. ISSN 1434-193X

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.20...

Related URL: http://dx.doi.org/10.1002/ejoc.201101424

Abstract

Herein we describe the synthesis of cis-/trans-3-aminotetrahydrofuran-2-carboxylic acids (cis-/trans-FAA) having a γ-methoxy group cis to the amine. The homo-oligomers of these two diastereomeric FAAs have been prepared. Preliminary investigation of their solution secondary structures revealed that they are the same as the homo-oligomers of the parent cis-/trans-FAA with the methoxy group only being a spectator substituent.

Item Type:Article
Source:Copyright of this article belongs to John Wiley & Sons, Inc.
Keywords:Amino Acids; Oxygen Heterocycles; Peptides; Helical structures
ID Code:106009
Deposited On:01 Feb 2018 16:53
Last Modified:01 Feb 2018 16:53

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