Prasad, Kavirayani R. ; Gholap, Shivajirao L. (2006) Stereoselective synthesis of (+)-goniothalesdiol The Journal of Organic Chemistry, 71 (9). pp. 3643-3645. ISSN 0022-3263
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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo060159f
Related URL: http://dx.doi.org/10.1021/jo060159f
Abstract
Stereoselective synthesis of antitumor tetrahydrofuran (+)-goniothalesdiol was achieved in high overall yield from (−)-D-tartaric acid. Key features include an FeCl3 mediated THF formation with very high selectivity. Synthesis of natural gonithalesdiol and its analogue 2,5-bis-epi-goniothalesdiol was achieved from a common intermediate.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 105845 |
| Deposited On: | 21 Dec 2017 12:02 |
| Last Modified: | 21 Dec 2017 12:02 |
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