Total synthesis of (+)-phomopsolide B

Prasad, Kavirayani R. ; Gutala, Phaneendra (2012) Total synthesis of (+)-phomopsolide B Tetrahedron, 68 (36). pp. 7489-7493. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tet.2012.06.002

Abstract

An enantiospecific total synthesis of polyhydroxy δ-pyrone natural product phomopsolide B is accomplished. The main feature of the synthesis is the installation of the required E-olefin by Horner–Emmons–Wordsworth reaction and the formation of the lactone involving Still–Gennari olefination followed by lactonization.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Phomopsolide B; Polyhydroxy Lactone; δ-Pyrone
ID Code:105692
Deposited On:21 Dec 2017 12:04
Last Modified:21 Dec 2017 12:04

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