Enantioselective synthesis of macrolactone core of the natural product Sch725674

Sunnam, Sunil Kumar ; Prasad, Kavirayani R. (2014) Enantioselective synthesis of macrolactone core of the natural product Sch725674 Tetrahedron, 70 (12). pp. 2096-2101. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tet.2014.02.008

Abstract

An enantioselective synthesis of the macrolactone core of natural product Sch725674 was accomplished from furfural. Key reactions in assembly of the macrolactone are the use of furan as a but-2-ene-dione equivalent and ring closing metathesis.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Macrolide; Total Synthesis; Natural Products; Sch725674
ID Code:105630
Deposited On:21 Dec 2017 12:04
Last Modified:21 Dec 2017 12:04

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