Deshpande, Sachin G. ; Pathak, Tanmaya Synthesis and synthetic applications of 1-(3-O-tosyl-β-D-glucopyranosyl) thymines: toward new classes of hexopyranosyl pyrimidines Tetrahedron Letters, 45 (10). pp. 2255-2258. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2003.12.153
Abstract
1-(2,4,6-Tri-O-acetyl-3-O-tosyl-β-D-glucopyranosyl) thymine has been synthesized by combining thymine with the appropriate carbohydrate. The availability of this key nucleoside made possible the synthesis of 2,2′-O-anhydro-(4,6-O-phenylmethylene-β-D-altropyranosyl) thymine and 1-(2,3-O-anhydro-4,6-O-phenylmethylene-β-D-mannopyranosyl) thymine. A wide range of modified hexopyranosyl nucleosides can be easily prepared from these functionalized starting materials.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Hexopyranosyl; Nucleosides; Modified; Allopyranosyl; Altropyranosyl; Azidonucleosides; Thionucleosides; Aminonucleosides |
| ID Code: | 104198 |
| Deposited On: | 17 Mar 2017 09:17 |
| Last Modified: | 17 Mar 2017 09:17 |
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