Diastereoselective michael initiated ring closure on vinyl sulfone-modified carbohydrates: a stereospecific and general route to α-substituted cyclopropanes.

Das, Indrajit ; Pal, Tarun K. ; Pathak, Tanmaya (2007) Diastereoselective michael initiated ring closure on vinyl sulfone-modified carbohydrates: a stereospecific and general route to α-substituted cyclopropanes. The Journal of Organic Chemistry, 72 (24). pp. 9181-9189. ISSN 0022-3263

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo701378d

Related URL: http://dx.doi.org/10.1021/jo701378d

Abstract

Suitably designed vinyl sulfone-modified furanosides act as substrates for Michael initiated ring closure reactions yielding cyclopropanated carbohydrates. The strategy is general in nature and gives access to cyclopropanes with predefined chiralities on three consecutive carbons with varying substitutions at the α-position.

Item Type:Article
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ID Code:104123
Deposited On:17 Mar 2017 09:35
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