DNA structure and human diseases

Raghavan, Sathees C. ; Lieber, Michael R. (2007) DNA structure and human diseases Frontiers in Bioscience, 12 . pp. 4402-4408. ISSN 1093-9946

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Abstract

Recently, multiple lines of evidences have shown that non-B DNA structures within the human genes may lead to chromosomal translocations, deletions and amplifications in cancer and other human diseases. In this review, we summarize the current literature on non-B DNA structures, and discuss their role in genomic instability and diseases.

Item Type:Article
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ID Code:103992
Deposited On:01 Feb 2018 10:10
Last Modified:01 Feb 2018 10:10

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