Templating effect of 1,5-disubstituted 1,2,3-triazole-linked disaccharides on size, shape and antibacterial activity of silver nanoparticles

Abstract

1,5-Disubstituted 1,2,3-triazole (1,5-DT) linked disaccharides were used in the modified Tollens method for the synthesis and stabilization of silver nanoparticles (AgNPs) for the first time. The templating effect of the triazole ring is evident from the spectral data. Unlike the naturally occurring disaccharides these disaccharides are stable and the formation of the corresponding dicarboxylate was established. AgNPs obtained from one of the disaccharides showed promising antimicrobial activity. The formation, shapes and antimicrobial activity of the AgNPs strongly depend on the molecular structure of the 1,5-DTs used.