Kumar, Niti ; Nielsen, Katrine E. ; Maiti, Souvik ; Petersen, Michael (2006) Triplex formation with α-L-LNA (α-l-ribo-configured locked nucleic acid) Journal of the American Chemical Society, 128 (1). pp. 14-15. ISSN 0002-7863
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Official URL: http://pubs.acs.org/doi/abs/10.1021/ja055483r
Related URL: http://dx.doi.org/10.1021/ja055483r
Abstract
Using UV melting and CD spectroscopy, we show that α-l-LNA-modified oligonucleotides possess the ability to form triplexes at pH 6.8 with significantly increased thermostability relative to DNA triplexes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 103384 |
| Deposited On: | 02 Feb 2018 03:47 |
| Last Modified: | 02 Feb 2018 03:47 |
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