Singh, Amit Raj ; Giri, Debaprasad ; Kumar, Sanjay (2009) Force induced unfolding of biopolymers in a cellular environment: a model study The Journal of Chemical Physics, 131 (6). Article ID 065103. ISSN 0021-9606
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Official URL: http://aip.scitation.org/doi/full/10.1063/1.319701...
Related URL: http://dx.doi.org/10.1063/1.3197010
Abstract
Effect of molecular crowding and confinement experienced by protein in the cell during unfolding has been studied by modeling a linear polymer chain on a percolation cluster. It is known that internal structure of the cell changes in time, however, they do not change significantly from their initial structure. In order to model this we introduce the correlation among the different disorder realizations. It was shown that the force-extension behavior for correlated disorder in both constant force ensemble and constant distance ensemble is significantly different than the one obtained in absence of molecular crowding.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Institute of Physics. |
| Keywords: | Percolation; Annealing; Probability Theory; Statistical Mechanics Models; Polymers |
| ID Code: | 102642 |
| Deposited On: | 02 Feb 2018 04:13 |
| Last Modified: | 02 Feb 2018 04:13 |
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