Gawade, S. P. ; Gaitonde, B. B. (1982) Isolation and characterisation of toxic components from the venom of the common Indian sea snake (Enhydrina schistosa) Toxicon, 20 (4). pp. 797-801. ISSN 0041-0101
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/004101...
Related URL: http://dx.doi.org/10.1016/0041-0101(82)90128-3
Abstract
Three neurotoxic components, enhydrotoxins a, b and c, were isolated by a three step procedure from the venom of the sea snake Enhydrina schistosa, caught in the Arabian sea. The i.v. LD50 values in mice were 0.042, 0.045 and 0.052 mg/kg, respectively. All three toxins irreversibly blocked neuromuscular transmission. Abolition of responses to acetylcholine indicated a post-synaptic site of action of these toxins. The molecular weight and amino acid composition of enhydrotoxin a are similar to values earlier reported for Enhydrina toxins.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 10246 |
| Deposited On: | 04 Nov 2010 06:49 |
| Last Modified: | 31 May 2011 11:46 |
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